Cloned (Comment) | Organism |
---|---|
expression in BL21 DE3 cells | Caenorhabditis elegans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | a zinc ion is present in a zinc finger motif | Caenorhabditis elegans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | Q9XW42 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Caenorhabditis elegans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + [human histone H2B peptide]-L-arginine | Caenorhabditis elegans PRMT-7 is able to methylate synthetic human histone H2B peptides containing residues 23-37. The C. elegans enzyme recognizes the human peptide better than the Caenorhabditis elegans peptide. The histone H2B R29K peptide reduces methylation counts to a level about 40%, of that of the wild type peptide sequence. The R31K and R33K mutant peptides further decrease the activity to about 10% and 22% respectively, signifying the importance of arginine residues in a sequential R-X-R motif | Caenorhabditis elegans | S-adenosyl-L-homocysteine + [human histone H2B peptide]-Nomega-methyl-L-arginine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PRMT-7 | - |
Caenorhabditis elegans |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
15 | - |
- |
Caenorhabditis elegans |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | 30 | the enzyme is much more active at 25°C than at 30°C | Caenorhabditis elegans |