Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.321 extracted from

  • Miranda, T.B.; Miranda, M.; Frankel, A.; Clarke, S.
    PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity (2004), J. Biol. Chem., 279, 22902-22907.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information truncated proteins consisiting of one of the two putative AdoMet-binding motifs are enzymatically inactive Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NVM4 isoform PRMT7
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no substrate: GST-fibrillarin fusion protein containing fibrillarin residues 1-148, substrate of isoforms PRMT1, PRMT3, PRMT4, PRMT5, EC 2.1.1.319. Isoform PRMT7 neither methylates myelin basic protein or histone H2A, in vitro substrates of PRMT5 Homo sapiens ?
-
?
S-adenosyl-L-methionine + GGPGGRGGPGG-NH2 substrate is a synthetic peptide Homo sapiens S-adenosyl-L-homocysteine + GGPGG-Nomega-methyl-RGGPGG enzyme catalyzes monomethylation of Arg-residues ?

Synonyms

Synonyms Comment Organism
PRMT7
-
Homo sapiens