Literature summary for 2.1.1.319 extracted from

Tang, J.; Frankel, A.; Cook, R.J.; Kim, S.; Paik, W.K.; Williams, K.R.; Clarke, S.; Herschman, H.R.
PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells (2000), J. Biol. Chem., 275, 7723-7730.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q63009	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-
liver	-	Rattus norvegicus	-
Rat-1 cell	isoform PRMT1 is the predominant protein arginine methyltransferase in RAT1 cells	Rattus norvegicus	-
testis	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + [GST-GAR protein]-L-arginine	-	Rattus norvegicus	S-adenosyl-L-homocysteine + [GST-GAR protein]-Nomega-methyl-L-arginine	-	?
S-adenosyl-L-methionine + [heterogeneous nuclear ribonucleoprotein A1]-Nomega-methyl-L-arginine	-	Rattus norvegicus	S-adenosyl-L-homocysteine + [heterogeneous nuclear ribonucleoprotein A1]-Nomega,Nomega-dimethyl-L-arginine	-	?

Synonyms

Synonyms	Comment	Organism
PRMT1	-	Rattus norvegicus

General Information

General Information	Comment	Organism
physiological function	PRMT1 contributes the major type I protein arginine methyltransferase enzyme activity present in mammalian cells and tissues	Rattus norvegicus

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Release 2023.1 (January 2023)