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Literature summary for 2.1.1.319 extracted from

  • Tang, J.; Gary, J.D.; Clarke, S.; Herschman, H.R.
    PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation (1998), J. Biol. Chem., 273, 16935-16945.
    View publication on PubMed
Search for more literature for 2.1.1.319

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm predominant localization Rattus norvegicus 5737
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
59400
-
 1 * 59400, calculated, 1 * 60000, SDS-PAGE Rattus norvegicus
60000
-
 1 * 59400, calculated, 1 * 60000, SDS-PAGE Rattus norvegicus
64000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus O70467
-
-

Source Tissue

Source Tissue Comment Organism Textmining
PC-12 cell constitutive expression Rattus norvegicus
-
Rat-1 cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isoform PRMT3 asymmetrically dimethylates arginine residues present both in the substrate GST-GAR and in substrate proteins present in hypomethylated extracts of a yeast rmt1 mutant that lacks type I arginine methyltransferase activity Rattus norvegicus ?
-
 ?
S-adenosyl-L-methionine + [GST-GAR protein]-L-arginine substrate is a fusion protein of Schistosoma japonicum glutathione S-transferase protein to the first 148 amino acids of human fibrillarin, containing 14 arginine residues in a glycine-rich region Rattus norvegicus S-adenosyl-L-homocysteine + [GST-GAR protein]-Nomega-methyl-L-arginine
-
 ?
S-adenosyl-L-methionine + [GST-GAR protein]-Nomega-methyl-L-arginine
-
 Rattus norvegicus S-adenosyl-L-homocysteine + [GST-GAR protein]-Nomega,Nomega-dimethyl-L-arginine
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 59400, calculated, 1 * 60000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
PRMT3
-
 Rattus norvegicus