Protein Variants | Comment | Organism |
---|---|---|
C478A | the polysome profile from the mutant reveals defect in 60S biogenesis and significant reduction in polysome fractions compared with isogenic wild type | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + cytosine2870 in 25S rRNA | Saccharomyces cerevisiae | the enzyme is responsible for the methylation at cytosine2870 of the 25S ribosomal RNA | S-adenosyl-L-homocysteine + 5-methylcytosine2870 in 25S rRNA | - |
? | |
S-adenosyl-L-methionine + cytosine2870 in 25S rRNA | Saccharomyces cerevisiae ATCC 204508 | the enzyme is responsible for the methylation at cytosine2870 of the 25S ribosomal RNA | S-adenosyl-L-homocysteine + 5-methylcytosine2870 in 25S rRNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P40991 | - |
- |
Saccharomyces cerevisiae ATCC 204508 | P40991 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + cytosine2870 in 25S rRNA | the enzyme is responsible for the methylation at cytosine2870 of the 25S ribosomal RNA | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + 5-methylcytosine2870 in 25S rRNA | - |
? | |
S-adenosyl-L-methionine + cytosine2870 in 25S rRNA | the enzyme is specific for cytosine2870 of the 25S ribosomal RNA | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + 5-methylcytosine2870 in 25S rRNA | - |
? | |
S-adenosyl-L-methionine + cytosine2870 in 25S rRNA | the enzyme is responsible for the methylation at cytosine2870 of the 25S ribosomal RNA | Saccharomyces cerevisiae ATCC 204508 | S-adenosyl-L-homocysteine + 5-methylcytosine2870 in 25S rRNA | - |
? | |
S-adenosyl-L-methionine + cytosine2870 in 25S rRNA | the enzyme is specific for cytosine2870 of the 25S ribosomal RNA | Saccharomyces cerevisiae ATCC 204508 | S-adenosyl-L-homocysteine + 5-methylcytosine2870 in 25S rRNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NOP2 | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
malfunction | the loss of m5C2870 affects ribosome synthesis and processing | Saccharomyces cerevisiae |