Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli K12 | Pseudomonas fluorescens |
expression in Escherichia coli K12 | Streptomyces lavendulae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + L-tyrosine | Streptomyces lavendulae | the enzyme is highly selective with regard to their natural substrate. The enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Saframycin (antibiotic) | S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine | - |
? | |
S-adenosyl-L-methionine + L-tyrosine | Pseudomonas fluorescens | the enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Safracin (antibiotic) | S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas fluorescens | - |
- |
- |
Streptomyces lavendulae | B0CN31 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | activity with L-DOPA is 1% of the activity with L-tyrosine | Streptomyces lavendulae | ? | - |
- |
|
additional information | activity with L-DOPA is 2% of the activity with L-tyrosine | Pseudomonas fluorescens | ? | - |
- |
|
S-adenosyl-L-methionine + D-tyrosine | 24% of the activity as compared to L-tyrosine | Streptomyces lavendulae | S-adenosyl-L-homocysteine + 3-methyl-D-tyrosine | - |
? | |
S-adenosyl-L-methionine + D-tyrosine | 64% of the activity as compared to L-tyrosine | Pseudomonas fluorescens | S-adenosyl-L-homocysteine + 3-methyl-D-tyrosine | - |
? | |
S-adenosyl-L-methionine + L-tyrosine | - |
Pseudomonas fluorescens | S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine | - |
? | |
S-adenosyl-L-methionine + L-tyrosine | the enzyme is highly selective with regard to their natural substrate. The enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Saframycin (antibiotic) | Streptomyces lavendulae | S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine | - |
? | |
S-adenosyl-L-methionine + L-tyrosine | the enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Safracin (antibiotic) | Pseudomonas fluorescens | S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine | - |
? | |
S-adenosyl-L-methionine + L-tyrosine | the enzyme is highly selective with regard to their natural substrate | Streptomyces lavendulae | S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SacF | - |
Pseudomonas fluorescens |
SfmM2 | - |
Streptomyces lavendulae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Pseudomonas fluorescens |
30 | - |
assay at | Streptomyces lavendulae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Pseudomonas fluorescens |
7 | - |
assay at | Streptomyces lavendulae |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Safracin (antibiotic) | Pseudomonas fluorescens |
physiological function | the enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Saframycin (antibiotic) | Streptomyces lavendulae |