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Literature summary for 2.1.1.301 extracted from

  • Claesen, J.; Bibb, M.
    Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides (2010), Proc. Natl. Acad. Sci. USA, 107, 16297-16302.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] Streptomyces sp.
-
S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin]
-
?
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] Streptomyces sp. OH-4156
-
S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin]
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces sp.
-
-
-
Streptomyces sp. OH-4156
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin]
-
Streptomyces sp. S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin]
-
?
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin]
-
Streptomyces sp. OH-4156 S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin]
-
?

Synonyms

Synonyms Comment Organism
CypM
-
Streptomyces sp.
S-adenosyl methionine-dependent methyltransferase
-
Streptomyces sp.