Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
expressio in HeLa cells | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | when expressed in HeLa cells the enzyme is enriched in the nuclear compartment | Mus musculus | 5634 | - |
nucleus | when expressed in HeLa cells the enzyme is enriched in the nuclear compartment | Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + N-terminal-Ala-Pro-Lys-[protein] | Mus musculus | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | S-adenosyl-L-homocysteine + N-terminal-N-methyl-N-Ala-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Ala-Pro-Lys-[protein] | Homo sapiens | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | S-adenosyl-L-homocysteine + N-terminal-N-methyl-N-Ala-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Pro-Pro-Lys-[protein] | Mus musculus | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Pro-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Pro-Pro-Lys-[protein] | Homo sapiens | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Pro-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Ser-Pro-Lys-[protein] | Mus musculus | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Ser-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Ser-Pro-Lys-[protein] | Homo sapiens | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Ser-Pro-Lys-[protein] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q5VVY1 | - |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | NRMT2 mRNA is enriched in the liver and in the skeletal muscle. Expressed at fairly low levels in all tissues examined | Mus musculus | - |
skeletal muscle | NRMT2 mRNA is enriched in the liver and in the skeletal muscle. Expressed at fairly low levels in all tissues examined | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + N-terminal-Ala-Pro-Lys-[protein] | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | Mus musculus | S-adenosyl-L-homocysteine + N-terminal-N-methyl-N-Ala-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Ala-Pro-Lys-[protein] | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | Homo sapiens | S-adenosyl-L-homocysteine + N-terminal-N-methyl-N-Ala-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Pro-Pro-Lys-[protein] | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | Mus musculus | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Pro-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Pro-Pro-Lys-[protein] | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | Homo sapiens | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Pro-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Ser-Pro-Lys-[protein] | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | Mus musculus | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Ser-Pro-Lys-[protein] | - |
? | |
S-adenosyl-L-methionine + N-terminal-Ser-Pro-Lys-[protein] | the enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal | Homo sapiens | S-adenosyl-L-homocysteine + N-terminal-N-methyl-Ser-Pro-Lys-[protein] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
METTL11B | - |
Mus musculus |
METTL11B | - |
Homo sapiens |
N-terminal monomethylase | - |
Mus musculus |
N-terminal monomethylase | - |
Homo sapiens |
NRMT2 | - |
Mus musculus |
NRMT2 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Homo sapiens |