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Literature summary for 2.1.1.297 extracted from

  • Pannekoek, Y.; Heurgue-Hamard, V.; Langerak, A.A.; Speijer, D.; Buckingham, R.H.; van der Ende, A.
    The N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase PrmC/HemK in Chlamydia trachomatis methylates class 1 release factors (2005), J. Bacteriol., 187, 507-511.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Chlamydia trachomatis PrmC methylates chlamydia peptide release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln ?
-
?
additional information Chlamydia trachomatis ATCC VR-902B PrmC methylates chlamydia peptide release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln ?
-
?
S-adenosyl-L-methionine + [peptide chain release factor 1]-L-glutamine Chlamydia trachomatis
-
S-adenosyl-L-homocysteine + [peptide chain release factor 1]-N5-methyl-L-glutamine
-
?
S-adenosyl-L-methionine + [peptide chain release factor 1]-L-glutamine Chlamydia trachomatis ATCC VR-902B
-
S-adenosyl-L-homocysteine + [peptide chain release factor 1]-N5-methyl-L-glutamine
-
?
S-adenosyl-L-methionine + [peptide chain release factor 2]-L-glutamine Chlamydia trachomatis
-
S-adenosyl-L-homocysteine + [peptide chain release factor 2]-N5-methyl-L-glutamine
-
?
S-adenosyl-L-methionine + [peptide chain release factor 2]-L-glutamine Chlamydia trachomatis ATCC VR-902B
-
S-adenosyl-L-homocysteine + [peptide chain release factor 2]-N5-methyl-L-glutamine
-
?

Organism

Organism UniProt Comment Textmining
Chlamydia trachomatis B0B9D1 serovar L2
-
Chlamydia trachomatis ATCC VR-902B B0B9D1 serovar L2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PrmC methylates chlamydia peptide release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ?
-
?
additional information PrmC methylates release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ?
-
?
additional information PrmC methylates chlamydia peptide release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ATCC VR-902B ?
-
?
additional information PrmC methylates release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ATCC VR-902B ?
-
?
S-adenosyl-L-methionine + [peptide chain release factor 1]-L-glutamine
-
Chlamydia trachomatis S-adenosyl-L-homocysteine + [peptide chain release factor 1]-N5-methyl-L-glutamine
-
?
S-adenosyl-L-methionine + [peptide chain release factor 1]-L-glutamine
-
Chlamydia trachomatis ATCC VR-902B S-adenosyl-L-homocysteine + [peptide chain release factor 1]-N5-methyl-L-glutamine
-
?
S-adenosyl-L-methionine + [peptide chain release factor 2]-L-glutamine
-
Chlamydia trachomatis S-adenosyl-L-homocysteine + [peptide chain release factor 2]-N5-methyl-L-glutamine
-
?
S-adenosyl-L-methionine + [peptide chain release factor 2]-L-glutamine
-
Chlamydia trachomatis ATCC VR-902B S-adenosyl-L-homocysteine + [peptide chain release factor 2]-N5-methyl-L-glutamine
-
?

Synonyms

Synonyms Comment Organism
PrmC
-
Chlamydia trachomatis

General Information

General Information Comment Organism
physiological function chlamydial isoform PrmC expression suppresses the growth defect of a prmC knockout strain of Escherichia coli K-12. Overexpression of PrmC in Escherichia coli strongly retards growth to the level of neative control Chlamydia trachomatis