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Literature summary for 2.1.1.237 extracted from

  • Tsukada, S.; Anzai, Y.; Li, S.; Kinoshita, K.; Sherman, D.H.; Kato, F.
    Gene targeting for O-methyltransferase genes, mycE and mycF, on the chromosome of Micromonospora griseorubida producing mycinamicin with a disruption cassette containing the bacteriophage phi C31 attB attachment site (2010), FEMS Microbiol. Lett., 304, 148-156.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + mycinamicin III Micromonospora griseorubida the enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics S-adenosyl-L-homocysteine + mycinamicin IV
-
?

Organism

Organism UniProt Comment Textmining
Micromonospora griseorubida
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + mycinamicin III
-
Micromonospora griseorubida S-adenosyl-L-homocysteine + mycinamicin IV
-
?
S-adenosyl-L-methionine + mycinamicin III the enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics Micromonospora griseorubida S-adenosyl-L-homocysteine + mycinamicin IV
-
?

Synonyms

Synonyms Comment Organism
MycF
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Micromonospora griseorubida

General Information

General Information Comment Organism
malfunction construction of a MycF disrupion mutant. The disruption mutant mainly produces mycinamicin III Micromonospora griseorubida