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Literature summary for 2.1.1.202 extracted from

  • King, M.Y.; Redman, K.L.
    RNA methyltransferases utilize two cysteine residues in the formation of 5-methylcytosine (2002), Biochemistry, 41, 11218-11225.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
C424A organism containing the C424A mutation is not viable Saccharomyces cerevisiae
C478A organism containing the C478A mutation is viable Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information a catalytic model for the RNA m5C methyltransferases that utilizes both conserved cysteines. The TC-Cys is proposed to perform covalent catalysis while the PC-Cys plays an important role in product release Saccharomyces cerevisiae ?
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?

Synonyms

Synonyms Comment Organism
Ncl1p
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Saccharomyces cerevisiae