Cloned (Comment) | Organism |
---|---|
cloning of the gene and construction of enzyme deficient mice | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + glycine | Homo sapiens | key regulatory enzyme for methyl group metabolism by regulating the S-adenosyl-L-methionine/S-adenosyl-L-homocysteine ratio | S-adenosyl-L-homocysteine + N-methylglycine | - |
? | |
S-adenosyl-L-methionine + glycine | Mus musculus | key regulatory enzyme for methyl group metabolism by regulating the S-adenosyl-L-methionine/S-adenosyl-L-homocysteine ratio | S-adenosyl-L-homocysteine + N-methylglycine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
three cases of GNMT mutations known, all suffering from mild liver disease and display elevated methionine levels | - |
Mus musculus | Q9QXF8 | construction of GNMT knockout mice, loss of enzyme results in highly elevated levels of free methionine and S-adenosyl-L-methionine | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Mus musculus | - |
pancreas | - |
Homo sapiens | - |
pancreas | - |
Mus musculus | - |
prostate | - |
Homo sapiens | - |
prostate | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + glycine | - |
Mus musculus | S-adenosyl-L-homocysteine + N-methylglycine | - |
? | |
S-adenosyl-L-methionine + glycine | key regulatory enzyme for methyl group metabolism by regulating the S-adenosyl-L-methionine/S-adenosyl-L-homocysteine ratio | Homo sapiens | S-adenosyl-L-homocysteine + N-methylglycine | - |
? | |
S-adenosyl-L-methionine + glycine | key regulatory enzyme for methyl group metabolism by regulating the S-adenosyl-L-methionine/S-adenosyl-L-homocysteine ratio | Mus musculus | S-adenosyl-L-homocysteine + N-methylglycine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GNMT | - |
Homo sapiens |
GNMT | - |
Mus musculus |