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Literature summary for 2.1.1.20 extracted from
- Retinoic acid and glucocorticoid treatment induce hepatic glycine N-methyltransferase and lower plasma homocysteine concentrations in rats and rat hepatoma cells (2003), J. Nutr., 133, 3392-3398.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | all-trans-retinoic acid and dexamethasone independently induce GNMT in liver, thereby having substantial implications for the potential interaction of retinoic administration with diabetes | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | all-trans-retinoic acid and dexamethasone independently induce GNMT in liver, no effect on enzyme from pancreas | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| pancreas | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | all-trans-retinoic acid and dexamethasone independently induce GNMT in liver, no effect on enzyme from pancreas | Rattus norvegicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GNMT | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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