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Literature summary for 2.1.1.20 extracted from
- Purification and properties of pancreatic glycine N-methyltransferase (1992), J. Biol. Chem., 267, 24669-24674.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5-Methyltetrahydrofolate hexaglutamate | - |
Rattus norvegicus |  |
| 5-Methyltetrahydrofolate pentaglutamate | - |
Rattus norvegicus | |
| 5-Methyltetrahydrofolate triglutamate | - |
Rattus norvegicus | |
| 5-methyltetrahydrofolic acid | - |
Rattus norvegicus | |
| 5-Methyltetrahydropteroylpentaglutamate | - |
Rattus norvegicus | |
| folinic acid | - |
Rattus norvegicus | |
| iodoacetate | - |
Rattus norvegicus | |
| methotrexate | - |
Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 34000 | - |
x * 34000, SDS-PAGE | Rattus norvegicus |
| 135000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + glycine | Rattus norvegicus | regulates the ratio of S-adenosylmethionine to S-adenosylhomocysteine | S-adenosyl-L-homocysteine + sarcosine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.132 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + glycine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + sarcosine | - |
? | |
| S-adenosyl-L-methionine + glycine | regulates the ratio of S-adenosylmethionine to S-adenosylhomocysteine | Rattus norvegicus | S-adenosyl-L-homocysteine + sarcosine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 34000, SDS-PAGE | Rattus norvegicus |
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