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Literature summary for 2.1.1.185 extracted from
- The rlmB gene is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli (2001), J. Bacteriol., 183, 6957-6960.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | a DELTArlmB mutant lacks 2'-O-methylguanosine in 23S rRNA, the mutant does not show any ribosome assembly defects and is not outgrown by a wild-type strain even after 120 cell mass doublings | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + guanosine2251 in 23S rRNA | Escherichia coli | the enzyme is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli | S-adenosyl-L-homocysteine + 2'-O-methylguanosine2251 in 23S rRNA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P63177 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + guanosine2251 in 23S rRNA | - |
Escherichia coli | S-adenosyl-L-homocysteine + 2'-O-methylguanosine2251 in 23S rRNA | - |
? | |
| S-adenosyl-L-methionine + guanosine2251 in 23S rRNA | the enzyme is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli | Escherichia coli | S-adenosyl-L-homocysteine + 2'-O-methylguanosine2251 in 23S rRNA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| rlmB | - |
Escherichia coli |
| rRNA Gm2251 methyltransferase | - |
Escherichia coli |
| yifH | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | a DELTArlmB mutant lacks 2'-O-methylguanosine in 23S rRNA, the mutant does not show any ribosome assembly defects and is not outgrown by a wild-type strain even after 120 cell mass doublings | Escherichia coli |
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