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Literature summary for 2.1.1.182 extracted from

  • Cunningham, P.R.; Weitzmann, C.J.; Nurse, K.; Masurel, R.; van Knippenberg, P.H.; Ofengand, J.
    Site-specific mutation of the conserved m6(2)A m6(2)A residues of E. coli 16S ribosomal RNA. Effects on ribosome function and activity of the ksgA methyltransferase (1990), Biochim. Biophys. Acta, 1050, 18-26.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4 S-adenosyl-L-methionine + adenine1518/adenine1519 in 16S rRNA neither of the adenine residues is required for methylation of the other, ruling out any obligate order of methylation of A1518 and A1519. Mutation of either A1518 or A1519 to C, G or U has little effect on the ability of the mutant RNA to reconstitute a 30S ribosome containing a full complement of ribosomal proteins Escherichia coli 4 S-adenosyl-L-homocysteine + N6-dimethyladenine1518/N6-dimethyladenine1519 in 16S rRNA
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Synonyms

Synonyms Comment Organism
ksgA methyltransferase
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Escherichia coli