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Literature summary for 2.1.1.17 extracted from

  • Resseguie, M.; Song, J.; Niculescu, M.D.; da Costa, K.; Randall, T.A.; Zeisel, S.H.
    Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes (2007), FASEB J., 21, 2622-2632.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information 17-beta-estradiol induces the enzyme in hepatocytes Homo sapiens
additional information 17-beta-estradiol induces the enzyme in hepatocytes Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis including a estrogen response sequence, the PEMT gene has three unique transcription start sites, which are indicative of either multiple promoters and/or alternative splicing Homo sapiens
DNA and amino acid sequence determination and analysis including a estrogen response sequence, the PEMT gene has three unique transcription start sites, which are indicative of either multiple promoters and/or alternative splicing Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UBM1
-
-
Mus musculus Q61907 male C57BL/6J mice
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
Homo sapiens
-
hepatocyte
-
Mus musculus
-

Synonyms

Synonyms Comment Organism
PEMT
-
Homo sapiens
PEMT
-
Mus musculus

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Homo sapiens
S-adenosyl-L-methionine
-
Mus musculus