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Literature summary for 2.1.1.156 extracted from

  • Kimura, Y.; Kawasaki, S.; Yoshimoto, H.; Takegawa, K.
    Glycine betaine biosynthesized from glycine provides an osmolyte for cell growth and spore germination during osmotic stress in Myxococcus xanthus (2010), J. Bacteriol., 192, 1467-1470.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.156

Cloned(Commentary)

Cloned (Comment) Organism
gene gsmA, DNA and amino acid sequence determination and analysis, sequence comparison Myxococcus xanthus

Protein Variants

Protein Variants Comment Organism
additional information construction of a chromosomal gsmA gene disruption knockout mutant, phenotype, overview Myxococcus xanthus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
29500
-
 x * 29500, about, sequence calculation Myxococcus xanthus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + glycine Myxococcus xanthus
-
 S-adenosyl-L-homocysteine + sarcosine
-
 ?
S-adenosyl-L-methionine + sarcosine Myxococcus xanthus
-
 S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
 ?

Organism

Organism UniProt Comment Textmining
Myxococcus xanthus
-
 gene gsmA encodes a Gsm homologue protein
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + glycine
-
 Myxococcus xanthus S-adenosyl-L-homocysteine + sarcosine
-
 ?
S-adenosyl-L-methionine + sarcosine
-
 Myxococcus xanthus S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
 ?

Subunits

Subunits Comment Organism
? x * 29500, about, sequence calculation Myxococcus xanthus

Synonyms

Synonyms Comment Organism
glycine sarcosine methyltransferase
-
 Myxococcus xanthus
Gsm
-
 Myxococcus xanthus
GsmA
-
 Myxococcus xanthus
MXAN 7068
-
 Myxococcus xanthus

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
 Myxococcus xanthus

General Information

General Information Comment Organism
malfunction disruption of the gsmA gene, encoding Gsm homologue protein, generates a mutant that exhibits a longer lag period of growth and delayed spore germination under osmostress, it shows normal growth in CYE medium at 30°C, phenotype, overview Myxococcus xanthus
metabolism glycine sarcosine methyltransferase and sarcosine dimethylglycine methyltransferase, EC 2.1.1.157, catalyze glycine betaine synthesis from glycine Myxococcus xanthus