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Literature summary for 2.1.1.148 extracted from

  • Mishanina, T.V.; Koehn, E.M.; Conrad, J.A.; Palfey, B.A.; Lesley, S.A.; Kohen, A.
    Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase (2012), J. Am. Chem. Soc., 134, 4442-4448.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Thermotoga maritima Q9WYT0
-
-
Thermotoga maritima ATCC 43589 Q9WYT0
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Thermotoga maritima

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP + FADH2
-
Thermotoga maritima dTMP + tetrahydrofolate + FAD
-
?
5,10-methylenetetrahydrofolate + dUMP + FADH2
-
Thermotoga maritima ATCC 43589 dTMP + tetrahydrofolate + FAD
-
?

Synonyms

Synonyms Comment Organism
FDTS
-
Thermotoga maritima
flavin-dependent thymidylate synthase
-
Thermotoga maritima

Cofactor

Cofactor Comment Organism Structure
FAD
-
Thermotoga maritima