Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.132 extracted from

  • Roessner, C.A.; Huang, K.X.; Warren, M.J.; Raux, E.; Scott, A.I.
    Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. Shermanii) (2002), Microbiology, 148, 1845-1853.
    View publication on PubMed
Search for more literature for 2.1.1.132

Cloned(Commentary)

Cloned (Comment) Organism
genes cbiEGH and cbiT, the gene cbiE of Propionibacterium freudenreichii is organized in a single ORF with genes cbiH and cbiG, DNA and amino acid sequence determination and analysis, genetic organization, co-overexpression of enzymes and reconstruction of the anaerobic cobalamin biosynthetic pathway in Escherichia coli in a construct comprising several genes, overview Propionibacterium freudenreichii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Pseudomonas denitrificans (nom. rej.) the organism performs the aerobic cobalamin biosynthesis variant ?
-
 ?
additional information Propionibacterium freudenreichii the organism performs the anaerobic cobalamin biosynthesis variant, the gene cbiE of Propionibacterium freudenreichii is organized in a single ORF with genes cbiH and cbiG, overview ?
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ Propionibacterium freudenreichii methylation and decarboxylation are catalyzed by 2 different enzymes in Propionibacterium freudenreichii, encoded by gene cbiE, organized in a orf/single gene with cbiG and cbiH, which is responsible for the methylations at C5 and C15, and by gene cbiT, which is responsible for the decarboxylation, steps of the anaerobic cobalamin biosynthesis, pathway overview S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ Pseudomonas denitrificans (nom. rej.) steps of the aerobic cobalamin biosynthesis, pathway overview S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Propionibacterium freudenreichii
-
 i.e. Propionibacterium shermanii, gene cbiE
-
Pseudomonas denitrificans (nom. rej.)
-
 gene cobL
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the organism performs the aerobic cobalamin biosynthesis variant Pseudomonas denitrificans (nom. rej.) ?
-
 ?
additional information the organism performs the anaerobic cobalamin biosynthesis variant, the gene cbiE of Propionibacterium freudenreichii is organized in a single ORF with genes cbiH and cbiG, overview Propionibacterium freudenreichii ?
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ methylation and decarboxylation are catalyzed by 2 different enzymes in Propionibacterium freudenreichii, encoded by gene cbiE, organized in a orf/single gene with cbiG and cbiH, which is responsible for the methylations at C5 and C15, and by gene cbiT, which is responsible for the decarboxylation, steps of the anaerobic cobalamin biosynthesis, pathway overview Propionibacterium freudenreichii S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ steps of the aerobic cobalamin biosynthesis, pathway overview Pseudomonas denitrificans (nom. rej.) S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ methylation and decarboxylation are catalyzed by 2 different enzymes in Propionibacterium freudenreichii, encoded by gene cbiE, organized in a orf/single gene with cbiG and cbiH, which is responsible for the methylations at C5 and C15, and by gene cbiT, which is responsible for the decarboxylation, overview Propionibacterium freudenreichii S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
 ?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ methylation at C5 and C15, and decarboxylation Pseudomonas denitrificans (nom. rej.) S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
 ?