Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | an integral membrane protein | Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MDA-MB-231 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine | - |
Homo sapiens | S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Icmt | - |
Homo sapiens |
isoprenylcysteine carboxylmethyltransferase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | cell migration and adhesion are impaired by enzyme inhibition (the actin cytoskeleton remains unorganized and lacks peripgeral actin filaments and stress fiber formation in the interior of the cell) | Homo sapiens |
physiological function | isoprenylcysteine carboxylmethyltransferase plays a role in cell migration and adhesion | Homo sapiens |