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Literature summary for 2.1.1.100 extracted from

  • Boivin, D.; Lin, W.; Beliveau, R.
    Essential arginine residues in isoprenylcysteine protein carboxyl methyltransferase (1997), Biochem. Cell Biol., 75, 63-69.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1-ethyl-3-(3-dimethylaminopropyl)carbodiimide 22% inhibition Rattus norvegicus
4-hydroxyphenylglyoxal 48% inhibition Rattus norvegicus
diethylpyrocarbonate 96% inhibition Rattus norvegicus
iodoacetic acid 16% inhibition Rattus norvegicus
N,N'-dicyclohexylcarbodiimide 76% inhibition Rattus norvegicus
N-bromosuccinimide 56% inhibition in the presence of S-adenosyl-L-homocysteine, 87% inhibition in the absence of S-adenosyl-L-homocysteine Rattus norvegicus
N-ethylmaleimide 2 mM, 94% inhibition after preincubation for 30 min, 45% inhibition in the presence of S-adenosyl-L-homocysteine Rattus norvegicus
Phenylglyoxal 74% inhibition, inhibition increases with the alkanity of the preincubation medium, S-adenosyl-L-methionine protects against inhibition Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney cortex Rattus norvegicus
-

pH Stability

pH Stability pH Stability Maximum Comment Organism
5.5 9.5 stable Rattus norvegicus