Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | reduction of Se(VI) to Se(0) via Se(IV) | ? | - |
? | |
selenate + reduced acceptor | Escherichia coli | - |
selenite + H2O + acceptor | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
ECISC-202 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | reduction of Se(VI) to Se(0) via Se(IV) | Escherichia coli | ? | - |
? | |
selenate + reduced acceptor | - |
Escherichia coli | selenite + H2O + acceptor | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | the selenate reductase in Escherichia coli is a multisubunit enzyme predicted to bind Fe-S clusters | Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
in vivo assay at | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
iron-sulfur center | activity of genes iscU or hscB in the Isc iron-sulfur cluster biosynthesis pathway is required for formation of selenate reductase activity in vivo | Escherichia coli |
General Information | Comment | Organism |
---|---|---|
metabolism | activity of genes iscU or hscB in the Isc iron-sulfur cluster biosynthesis pathway is required for formation of selenate reductase activity in vivo. Mutant strains JW2513 and JW2511 devoid of either the iscU or hscB gene in the Isc ironsulfur cluster biosynthesis pathway lose the ability to reduce selenate, phenotypes, overview. Genetic complementation by the wildtype sequences restored selenate reductase activity. The Isc biosynthetic system plays a key role in selenate reductase Fe-S cofactor assembly and is essential for enzyme activity | Escherichia coli |