Literature summary for 1.8.99.5 extracted from

Oliveira, T.F.; Vonrhein, C.; Matias, P.M.; Venceslau, S.S.; Pereira, I.A.; Archer, M.
The crystal structure of Desulfovibrio vulgaris dissimilatory sulfite reductase bound to DsrC provides novel insights into the mechanism of sulfate respiration (2008), J. Biol. Chem., 283, 34141-34149.

Cloned(Commentary)

Cloned (Comment)	Organism
structure with the alpha and beta subunits bound to the DsrC protein. The alpha2beta2gamma2 assembly contains two siroheme-[4Fe4S] cofactors bound by DsrB, two sirohydrochlorins and two [4Fe-4S]-centers bound by DsrA, and another four [4Fe-4S]-centers in the ferredoxin domains. A sulfite molecule, coordinating the siroheme, is found at the active site. The DsrC protein is bound in a cleft between DsrA and DsrB with its conserved C-terminal cysteine reaching the distal side of the siroheme. The process of sulfite reduction may involve DsrAB, DsrC, and the DsrMKJOP membrane complex (a membrane complex with putative disulfide/thiol reductase activity), in which two of the six electrons for reduction of sulfite derive from the membrane quinone pool	Desulfovibrio vulgaris

Cloned (Comment)

Organism

structure with the alpha and beta subunits bound to the DsrC protein. The alpha2beta2gamma2 assembly contains two siroheme-[4Fe4S] cofactors bound by DsrB, two sirohydrochlorins and two [4Fe-4S]-centers bound by DsrA, and another four [4Fe-4S]-centers in the ferredoxin domains. A sulfite molecule, coordinating the siroheme, is found at the active site. The DsrC protein is bound in a cleft between DsrA and DsrB with its conserved C-terminal cysteine reaching the distal side of the siroheme. The process of sulfite reduction may involve DsrAB, DsrC, and the DsrMKJOP membrane complex (a membrane complex with putative disulfide/thiol reductase activity), in which two of the six electrons for reduction of sulfite derive from the membrane quinone pool

Desulfovibrio vulgaris

Organism

Organism	UniProt	Comment	Textmining
Desulfovibrio vulgaris	P45574 and P45575	P45574 i.e. subunit alpha, P45575 i.e. subunit beta	-
Desulfovibrio vulgaris Hildenborough	P45574 and P45575	P45574 i.e. subunit alpha, P45575 i.e. subunit beta	-

Synonyms

Synonyms	Comment	Organism
DsvA	-	Desulfovibrio vulgaris
DsvB	-	Desulfovibrio vulgaris

Cofactor

Cofactor	Comment	Organism	Structure
siroheme	protein complex contains two siroheme-[4Fe4S] cofactors bound by subunit DsrB, two sirohydrochlorins and two [4Fe-4S]-centers bound by subunit DsrA, and another four [4Fe-4S]-centers in the ferredoxin domains	Desulfovibrio vulgaris
[4Fe-4S]-center	protein complex contains two siroheme-[4Fe4S] cofactors bound by subunit DsrB, two sirohydrochlorins and two [4Fe-4S]-centers bound by subunit DsrA, and another four [4Fe-4S]-centers in the ferredoxin domains	Desulfovibrio vulgaris