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Literature summary for 1.8.98.5 extracted from

  • Holmes, D.; Rotaru, A.; Ueki, T.; Shrestha, P.; Ferry, J.; Lovley, D.
    Electron and proton flux for carbon dioxide reduction in Methanosarcina barkeri during direct interspecies electron transfer (2018), Front. Microbiol., 9, 3109 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.8.98.5

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+ Methanosarcina barkeri
-
 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+ Methanosarcina barkeri MS
-
 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+ Methanosarcina barkeri DSM 800
-
 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+ Methanosarcina barkeri MS DSM 800
-
 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?

Organism

Organism UniProt Comment Textmining
Methanosarcina barkeri
-
-
-
Methanosarcina barkeri MS DSM 800
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture coculture of Methanosarcina barkeri with Pelobacter carbinolicus, transcriptome analysis, overview. Out of the 3809 predicted protein-coding genes in the Methanosarcina barkeri MS genome, 1912 and 1909 genes have expression levels that are higher than the median in HIT-grown cells, respectively Methanosarcina barkeri
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+
-
 Methanosarcina barkeri 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+
-
 Methanosarcina barkeri MS 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+
-
 Methanosarcina barkeri DSM 800 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+
-
 Methanosarcina barkeri MS DSM 800 2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?

Cofactor

Cofactor Comment Organism Structure
Ferredoxin
-
 Methanosarcina barkeri

General Information

General Information Comment Organism
metabolism generalized model for electron and proton flux during hydrogen interspecies electron transfer (HIT) and direct interspecies electron transfer (DIET) with growth on ethanol as an example, overview. H2 diffusion shuttles both electrons and protons between cells and carries both electrons and protons into the cell when cytoplasmic electron acceptors are reduced. The transcriptome reflects faster growth during HIT and possible greater importance of membrane and outer-surface proteins during DIET, but no specific upregulation of hydrogenase genes in response to growth via HIT Methanosarcina barkeri
physiological function the transcriptome of Methanosarcina barkeri grown via DIET in co-culture with Geobacter metallireducens compared with its transcriptome when grown via H2 interspecies transfer (HIT) with Pelobacter carbinolicus shows that transcripts for the F420H2 dehydrogenase (Fpo) and the heterodisulfide reductase, HdrABC, are more abundant during growth on DIET. In HIT, H2 simultaneously transports both electrons and protons as the H2 diffuses between the two partners. When the H2 is oxidized in the cytoplasm with electron transfer to an electron acceptor, protons are also released and are immediately available to balance the negative charge transferred to the electron acceptor. This maintains charge balance within the cell Methanosarcina barkeri