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Literature summary for 1.8.4.2 extracted from

  • Philipps, B.; Glockshuber, R.
    Randomization of the entire active-site helix alpha 1 of the thiol-disulfide oxidoreductase DsbA from Escherichia coli (2002), J. Biol. Chem., 277, 43050-43057.
    View publication on PubMed
Search for more literature for 1.8.4.2

Cloned(Commentary)

Cloned (Comment) Organism
enzyme variants Escherichia coli

Protein Variants

Protein Variants Comment Organism
H32PY34R/Q35L/F36I/E37Y active variant Escherichia coli
P31H/H32A/Y34G/Q35L/F36R/E37Y active variant Escherichia coli
P31H/H32D/Y34S/Q35E/E37S active variant Escherichia coli
P31H/H32T/Y34A/Q35S/F36T/E37R inactive variant Escherichia coli
P31K/Y34P/Q35V/F36P/E37T inactive variant Escherichia coli
P31R/H32G/Y34N/Q35K/F36L/E37A semi-active variant Escherichia coli
P31R/H32I/Y34F/F36V/E37P inactive variant Escherichia coli
P31R/H32S/Y34C/Q35T/F36Y/E37R semi-active variant Escherichia coli
P31Y/H32E/Y34T/Q35A/F36D/E37H inactive variant Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli the enzyme is required for efficient disulfide bond formation in the periplasm ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is required for efficient disulfide bond formation in the periplasm Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
DcbA
-
 Escherichia coli