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Literature summary for 1.8.4.12 extracted from

  • Bos, J.; Duverger, Y.; Thouvenot, B.; Chiaruttini, C.; Branlant, C.; Springer, M.; Charpentier, B.; Barras, F.
    The sRNA RyhB regulates the synthesis of the Escherichia coli methionine sulfoxide reductase MsrB but not MsrA (2013), PLoS ONE, 8, e63647 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Escherichia coli P0A746
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Expression

Organism Comment Expression
Escherichia coli sRNA RyhB is a direct regulator of the MsrB. RyhB down-regulates MsrB transcripts along with Hfq and RNaseE proteins. Mutations in the ryhB, fur, hfq, or RNaseE-encoded genes result in iron-insensitive expression of MsrB. RyhB pairing to msrB mRNA prevents efficient ribosome binding and thereby inhibits translation initiation. Both RyhB-pairing sites are required to decrease msrB expression additional information