Literature summary for 1.8.4.12 extracted from

Saha, S.; Hashino, M.; Suzuki, J.; Uda, A.; Watanabe, K.; Shimizu, T.; Watarai, M.
Contribution of methionine sulfoxide reductase B (MsrB) to Francisella tularensis infection in mice (2017), FEMS Microbiol. Lett., 364, fnw260.

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Organism

Organism	UniProt	Comment	Textmining
Francisella tularensis subsp. holarctica	A0A0B3VNT0	-	-

General Information

General Information	Comment	Organism
physiological function	an mMrB mutant exhibits decreased in vitro growth, exogenous oxidative stress resistance and intracellular growth in macrophages. A double mutant lacking both MsrA, EC 1.8.1.11, and MsrB exhibits the same characteristics as the MsrB mutant. The bacterial count of the MsrB mutant is significantly lower than that of the wild-type strain in the liver and spleen of mice	Francisella tularensis subsp. holarctica

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Release 2023.1 (January 2023)