Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-methionine (R)-sulfoxide + thioredoxin | Staphylococcus aureus | MsrB is specific for the (R)-form of the substrate | L-methionine + thioredoxin disulfide + H2O | - |
? | |
additional information | Staphylococcus aureus | the MsrA1/MsrB system is physiologically more significant in Staphylococcus aureus than MsrA2 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
strains RN450 and BB270, and derivatives, 1 gene msrB | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000029 | - |
wild-type strain RN450, substrate L-methionine (R)-sulfoxide | Staphylococcus aureus |
0.00003 | - |
msrA2 knockout strain RN450, substrate L-methionine (R)-sulfoxide | Staphylococcus aureus |
0.0012 | - |
msrA1 knockout strain RN450, substrate L-methionine (R)-sulfoxide | Staphylococcus aureus |
0.0015 | - |
msrA1/msrA2 double knockout strain RN450, substrate L-methionine (R)-sulfoxide | Staphylococcus aureus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-methionine (R)-sulfoxide + thioredoxin | MsrB is specific for the (R)-form of the substrate | Staphylococcus aureus | L-methionine + thioredoxin disulfide + H2O | - |
? | |
additional information | the MsrA1/MsrB system is physiologically more significant in Staphylococcus aureus than MsrA2 | Staphylococcus aureus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
methionine sulfoxide reductase | - |
Staphylococcus aureus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Staphylococcus aureus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Staphylococcus aureus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thioredoxin | - |
Staphylococcus aureus |