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Literature summary for 1.8.4.11 extracted from

  • Trivedi, R.N.; Agarwal, P.; Kumawat, M.; Pesingi, P.K.; Gupta, V.K.; Goswami, T.K.; Mahawar, M.
    Methionine sulfoxide reductase A (MsrA) contributes to Salmonella Typhimurium survival against oxidative attack of neutrophils (2015), Immunobiology, 220, 1322-1327 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
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General Information

General Information Comment Organism
physiological function a MsrA gene deletion strain grows normally in in vitro broth culture. The strain shows high susceptibility to very low concentrations of HOCl which is restored (at least in part) by plasmid based complementation. The MsrA gene deletion strain is hypersensitive to the granules isolated from neutrophils and significantly more susceptible to neutrophil mediated killing than wild-type Salmonella enterica subsp. enterica serovar Typhimurium