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Literature summary for 1.8.4.11 extracted from
- A molecular dynamics and quantum mechanics/molecular mechanics study of the catalytic reductase mechanism of methionine sulfoxide reductase A: formation and reduction of a sulfenic acid (2013), Biochemistry, 52, 1814-1827.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-methionine (S)-sulfoxide + thioredoxin | Mycobacterium tuberculosis | - |
L-methionine + thioredoxin disulfide + H2O | - |
? |  |
| L-methionine (S)-sulfoxide + thioredoxin | Mycobacterium tuberculosis H37Rv | - |
L-methionine + thioredoxin disulfide + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycobacterium tuberculosis | P9WJM5 | - |
- |
| Mycobacterium tuberculosis H37Rv | P9WJM5 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-methionine (S)-sulfoxide + thioredoxin | - |
Mycobacterium tuberculosis | L-methionine + thioredoxin disulfide + H2O | - |
? | |
| L-methionine (S)-sulfoxide + thioredoxin | - |
Mycobacterium tuberculosis H37Rv | L-methionine + thioredoxin disulfide + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| methionine sulfoxide reductase | - |
Mycobacterium tuberculosis |
| MsrA | - |
Mycobacterium tuberculosis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thioredoxin | - |
Mycobacterium tuberculosis | |
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Release 2023.1 (January 2023)
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