Literature summary for 1.8.3.7 extracted from

Roeser, D.; Preusser-Kunze, A.; Schmidt, B.; Gasow, K.; Wittmann, J.G.; Dierks, T.; von Figura, K.; Rudolph, M.G.
A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme (2006), Proc. Natl. Acad. Sci. USA, 103, 81-86 .

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Crystallization (Commentary)

Crystallization (Comment)	Organism
using 20-25% (w/v) PEG 4000/0.1 M Tris-HCl, pH 8.0-9.0, 0.2-0.3 M CaCl2	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
C336S	active site mutant	Homo sapiens
C341S	active site mutant	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	-	Homo sapiens	5783	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
a [sulfatase]-L-cysteine + O2 + a thiol	Homo sapiens	-	a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q8NBK3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HT-1080 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
a [sulfatase]-L-cysteine + O2 + a thiol	-	Homo sapiens	a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O	-	?

Synonyms

Synonyms	Comment	Organism
FGE	-	Homo sapiens

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Release 2023.1 (January 2023)