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Literature summary for 1.8.3.7 extracted from
- Eukaryotic formylglycine-generating enzyme catalyses a monooxygenase type of reaction (2015), FEBS J., 282, 3262-3274 .
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| O2 | for maximal activity the enzyme requires an O2 concentration of 9% (0.105 mM) | Homo sapiens |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Sf9 cells and High Five cells | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q8NBK3 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| HisTrap column chromatography and Superdex 200 gel filtration | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-MTDFYVPVSLCTPSRAALLTGRS-amide + O2 + dithiothreitol | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FGE | - |
Homo sapiens |
| FGly-generating enzyme | - |
Homo sapiens |
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