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Literature summary for 1.8.3.3 extracted from

  • Greenblatt, D.J.; Peters, D.E.; Oleson, L.E.; Harmatz, J.S.; MacNab, M.W.; Berkowitz, N.; Zinny, M.A.; Court, M.H.
    Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase (2009), Br. J. Clin. Pharmacol., 68, 920-927.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine ALT-2074, a catalytic mimic of glutathione oxidase, inhibits human cytochrome P450 3A isoforms in vitro Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ALT-2074, a catalytic mimic of glutathione oxidase, inhibits human cytochrome P450 3A isoforms in vitro Homo sapiens ?
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