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Literature summary for 1.8.1.B1 extracted from

  • Kalita, P.; Shukla, H.; Shukla, R.; Tripathi, T.
    Biochemical and thermodynamic comparison of the selenocysteine containing and non-containing thioredoxin glutathione reductase of Fasciola gigantica (2018), Biochim. Biophys. Acta Gen. Subj., 1862, 1306-1316 .
    View publication on PubMed
Search for more literature for 1.8.1.B1

Cloned(Commentary)

Cloned (Comment) Organism
expresion in Escherichia coli BL21 (DE3) Fasciola gigantica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
66000
-
 SDS-PAGE Fasciola gigantica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutathione disulfide + NADPH + H+ Fasciola gigantica
-
 2 glutathione + NADP+
-
 ?
thioredoxin disulfide + NADPH + H+ Fasciola gigantica
-
 thioredoxin + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Fasciola gigantica
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Fasciola gigantica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione disulfide + NADPH + H+
-
 Fasciola gigantica 2 glutathione + NADP+
-
 ?
thioredoxin disulfide + NADPH + H+
-
 Fasciola gigantica thioredoxin + NADP+
-
 ?

Subunits

Subunits Comment Organism
? x * 66000, SDS-PAGE Fasciola gigantica

Synonyms

Synonyms Comment Organism
thioredoxin glutathione reductase
-
 Fasciola gigantica

General Information

General Information Comment Organism
physiological function the enzyme plays an indispensible role in the redox biochemistry of parasitic flukes Fasciola gigantica