Application | Comment | Organism |
---|---|---|
medicine | the enzyme presents a target for anti-schistosomiasis drug development | Schistosoma mansoni |
Cloned (Comment) | Organism |
---|---|
recombinant enzyme with a fused bacterial-type SECIS element is expressed in Escherichia coli strain BL21(DE3) | Schistosoma mansoni |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Schistosoma mansoni | the parasite-specific enzyme thioredoxin glutathione reductase is a component of the defense system | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schistosoma mansoni | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
1536-well based kinetic absorbance assay for thioredoxin glutathione reductase. The assay uses the catalytic reduction of DTNB by NADPH in the presence of thioredoxin glutathione reductase | Schistosoma mansoni |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | - |
Schistosoma mansoni | ? | - |
? | |
additional information | the parasite-specific enzyme thioredoxin glutathione reductase is a component of the defense system | Schistosoma mansoni | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TGR | - |
Schistosoma mansoni |
thioredoxin glutathione reductase | - |
Schistosoma mansoni |