Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Anopheles gambiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0085 | - |
thioredoxin | thioredoxin-1 from Anopheles gambiae, pH 7.4 | Anopheles gambiae | |
0.009 | - |
thioredoxin | thioredoxin-2 from Drosophila melanogaster, pH 7.4 | Anopheles gambiae | |
0.033 | - |
thioredoxin | thioredoxin-1 from Plasmodium falciparum, pH 7.4 | Anopheles gambiae | |
0.7 | - |
5,5'-dithiobis(2-nitrobenzoic acid) | pH 7.4 | Anopheles gambiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | not a selenoenzyme, but instead contains a highly unusual redox-active Cys-Cys sequence | Anopheles gambiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Anopheles gambiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Anopheles gambiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | - |
Anopheles gambiae | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
thioredoxin disulfide + NADPH | thioredoxin-1 from Anopheles gambiae or Plasmodium falciparum, thioredoxin-2 from Drosophila melanogaster | Anopheles gambiae | thioredoxin + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
thioredoxin reductase-1 | - |
Anopheles gambiae |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5.5 | - |
5,5'-dithiobis(2-nitrobenzoic acid) | pH 7.4 | Anopheles gambiae | |
14.3 | - |
thioredoxin | thioredoxin-2 from Drosophila melanogaster, pH 7.4 | Anopheles gambiae | |
15.4 | - |
thioredoxin | thioredoxin-1 from Anopheles gambiae, pH 7.4 | Anopheles gambiae | |
15.7 | - |
thioredoxin | thioredoxin-1 from Plasmodium falciparum, pH 7.4 | Anopheles gambiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | contains FAD | Anopheles gambiae | |
NADPH | - |
Anopheles gambiae |