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Literature summary for 1.8.1.9 extracted from

  • Sun, Q.A.; Zappacosta, F.; Factor, V.M.; Wirth, P.J.; Hatfield, D.L.; Gladyshev, V.N.
    Heterogeneity within animal thioredoxin reductases. Evidence for alternative first exon splicing (2001), J. Biol. Chem., 276, 3106-3114.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
nucleotide sequence analysis and comparison Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Drosophila melanogaster 5829
-
cytosol
-
Mus musculus 5829
-
cytosol
-
Homo sapiens 5829
-
cytosol isoform TR1 Rattus norvegicus 5829
-
cytosol isoform TR1 Mus musculus 5829
-
cytosol isoform TR1 Drosophila melanogaster 5829
-
mitochondrion
-
Drosophila melanogaster 5739
-
mitochondrion
-
Homo sapiens 5739
-
mitochondrion isoform TR3 Mus musculus 5739
-
mitochondrion isoform TR3 Rattus norvegicus 5739
-
mitochondrion isoform TR2 Drosophila melanogaster 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
selenocysteine
-
Mus musculus
selenocysteine
-
Homo sapiens
selenocysteine
-
Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
67000
-
2 * 67000, isoform TR1, SDS-PAGE Rattus norvegicus
67000
-
2 * 67000, isoform TR1, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
isoform TR1 and TR2
-
Drosophila melanogaster P91938
-
-
Homo sapiens
-
cell line JPX9
-
Homo sapiens
-
3 different isoforms TR1, TR2, TR3
-
Homo sapiens Q9NNW7
-
-
Mus musculus
-
-
-
Mus musculus
-
3 isoforms TR1, TR2, TR3
-
Mus musculus Q9JMH6
-
-
Rattus norvegicus
-
3 isoforms TR1, TR2, TR3
-
Rattus norvegicus
-
RN5CATOMT
-

Purification (Commentary)

Purification (Comment) Organism
-
Mus musculus
-
Homo sapiens
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-
liver isoform TR1, normal and tumor Mus musculus
-
prostate gland isoform TR1 Rattus norvegicus
-

Subunits

Subunits Comment Organism
dimer 2 * 67000, isoform TR1, SDS-PAGE Rattus norvegicus
dimer 2 * 67000, isoform TR1, SDS-PAGE Mus musculus
dimer 2 * 55000-57000, isoforms TR1 and TR3, SDS-PAGE Mus musculus
dimer 2 * 55000-57000, isoforms TR1 and TR3, SDS-PAGE Homo sapiens
dimer 2 * 55000-57000, isoforms TR1 and TR3, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
TR
-
Mus musculus
TR
-
Homo sapiens
TR
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
FAD
-
Drosophila melanogaster
FAD
-
Mus musculus
FAD
-
Homo sapiens
FAD
-
Rattus norvegicus
NADPH
-
Drosophila melanogaster
NADPH
-
Mus musculus
NADPH
-
Homo sapiens
NADPH
-
Rattus norvegicus