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Literature summary for 1.8.1.9 extracted from

  • Schallreuter, K.U.; Wood, J.M.
    Calcium regulates thioredoxin reductase in human metastatic melanoma (1989), Biochim. Biophys. Acta, 997, 242-247.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ non-reversible by EDTA Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell metastatic melanotic Homo sapiens
-
melanoma cell amelanotic Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH i.e. DTNB Homo sapiens 2-nitro-5-thiobenzoate + NADP+
-
?
thioredoxin + NADP+
-
Homo sapiens thioredoxin disulfide + NADPH
-
?

Synonyms

Synonyms Comment Organism
TR
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Homo sapiens