Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3'-hydroxy-4'-O-methylisoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1->2)]-beta-D-glucopyranoside | - |
Bos taurus | |
hypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1->2)]-beta-D-glucopyranoside | - |
Bos taurus | |
isoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1->2)]-beta-D-glucopyranoside | - |
Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione disulfide + NADPH + H+ | Bos taurus | - |
glutathione + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
2',5'-ADP Sepharose 4B affinity chromatography and DEAE Sepharose column chromatography | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
renal cortex | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione disulfide + NADPH + H+ | - |
Bos taurus | glutathione + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EC 1.6.4.2 | formerly | Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
flavin | - |
Bos taurus | |
NADPH | - |
Bos taurus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.177 | - |
in 100 mM sodium phosphate buffer, pH 7.4, at 37°C | Bos taurus | hypolaetin 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1->2)]-beta-D-glucopyranoside | |
0.295 | - |
in 100 mM sodium phosphate buffer, pH 7.4, at 37°C | Bos taurus | 3'-hydroxy-4'-O-methylisoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1->2)]-beta-D-glucopyranoside | |
0.372 | - |
in 100 mM sodium phosphate buffer, pH 7.4, at 37°C | Bos taurus | isoscutellarein 7-O-[6'''-O-acetyl-beta-D-allopyranosyl-(1->2)]-beta-D-glucopyranoside |