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Literature summary for 1.8.1.7 extracted from
- Glutathione peroxidase and glutathione reductase activities are partially responsible for determining the susceptibility of cells to oxidative stress (2006), Toxicology, 226, 126-130.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| C6 glioma cell | - |
Rattus norvegicus | - |
| Hep-G2 cell | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.07 | - |
in C6 glioma cells, pH and temperature not specified in the publication | Rattus norvegicus |
| 5.63 | - |
in HepG2 cells, pH and temperature not specified in the publication | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione disulfide + NADPH + H+ | - |
Homo sapiens | glutathione + NADP+ | - |
? |  |
| glutathione disulfide + NADPH + H+ | - |
Rattus norvegicus | glutathione + NADP+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutathione reductase | - |
Homo sapiens |
| glutathione reductase | - |
Rattus norvegicus |
| GR | - |
Homo sapiens |
| GR | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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