Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Nicotine | 0.5 mg/kg, 11.8% enhancement of enzymatic activity in brain | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | vitamin E restores the inhibition of glutathione reductase due to nicotine administration in liver, lung, heart, stomach and kidney tissue, but not in testicle tissue | Rattus norvegicus | |
Nicotine | 0.5 mg/kg, significant inhibition of enzymatic activity in liver (61.5%), lung (65%), heart (70.5%), stomach (72.5%), kidney (64%) and testicle (71.5%) | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate fractionation, 2',5'-ADP Sepharose 4B affinity chromatography and Sephadex G-200 gel filtration | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
heart | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
lung | - |
Rattus norvegicus | - |
muscle | - |
Rattus norvegicus | - |
stomach | - |
Rattus norvegicus | - |
testicle | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
glutathione reductase | - |
Rattus norvegicus |
glutathione: NADP(+) oxidoreductase | - |
Rattus norvegicus |
GR | - |
Rattus norvegicus |