BRENDA - Enzyme Database
show all sequences of 1.8.1.3

Oxidation of hypotaurine in rat liver

Sumizu, K.; Biochim. Biophys. Acta 63, 210 - 212 (1962)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
2-mercaptoethanolamine
1 mM
Rattus norvegicus
cysteine
1 mM
Rattus norvegicus
Inhibitors
Inhibitors
Commentary
Organism
Structure
ammonium sulfate
10 mM
Rattus norvegicus
KCN
0.1 mM
Rattus norvegicus
phosphate
10 mM
Rattus norvegicus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
hypotaurine + H2O + NAD+
Rattus norvegicus
metabolism of cysteine
taurine + NADH
-
Rattus norvegicus
?
Organism
Organism
UniProt
Commentary
Textmining
Rattus norvegicus
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
ammonium sulfate precipitation, dialysis
Rattus norvegicus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Rattus norvegicus
-
Storage Stability
Storage Stability
Organism
frozen., 0.1 M Tris-HCl, pH 7.4, 36 h 50% loss of activity, loses total activity within 4 days
Rattus norvegicus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
hypotaurine + H2O + NAD+
-
394698
Rattus norvegicus
taurine + NADH
-
394698
Rattus norvegicus
?
hypotaurine + H2O + NAD+
metabolism of cysteine
394698
Rattus norvegicus
taurine + NADH
-
394698
Rattus norvegicus
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
7.8
-
Rattus norvegicus
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Rattus norvegicus
NADP+
slightly effective
Rattus norvegicus
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
2-mercaptoethanolamine
1 mM
Rattus norvegicus
cysteine
1 mM
Rattus norvegicus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Rattus norvegicus
NADP+
slightly effective
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
ammonium sulfate
10 mM
Rattus norvegicus
KCN
0.1 mM
Rattus norvegicus
phosphate
10 mM
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
hypotaurine + H2O + NAD+
Rattus norvegicus
metabolism of cysteine
taurine + NADH
-
Rattus norvegicus
?
Purification (Commentary) (protein specific)
Commentary
Organism
ammonium sulfate precipitation, dialysis
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Rattus norvegicus
-
Storage Stability (protein specific)
Storage Stability
Organism
frozen., 0.1 M Tris-HCl, pH 7.4, 36 h 50% loss of activity, loses total activity within 4 days
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
hypotaurine + H2O + NAD+
-
394698
Rattus norvegicus
taurine + NADH
-
394698
Rattus norvegicus
?
hypotaurine + H2O + NAD+
metabolism of cysteine
394698
Rattus norvegicus
taurine + NADH
-
394698
Rattus norvegicus
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
7.8
-
Rattus norvegicus
Other publictions for EC 1.8.1.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
394698
Sumizu
Oxidation of hypotaurine in ra ...
Rattus norvegicus
Biochim. Biophys. Acta
63
210 - 212
1962
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