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Literature summary for 1.7.2.2 extracted from

  • Poock, S.R.; Leach, E.R.; Moir, J.W.; Cole, J.A.; Richardson, D.J.
    Respiratory detoxification of nitric oxide by the cytochrome c nitrite reductase of Escherichia coli (2002), J. Biol. Chem., 277, 23664-23669.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
periplasm
-
Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nitrite + 6 ferrocytochrome c + 7 H+ Escherichia coli
-
NH3 + 2 H2O + 6 ferricytochrome c
-
?
NO + 5 ferrocytochrome c + 5 H+ Escherichia coli important role for the enzyme in nitric oxide management in oxygen-limited environments. Nitric oxide is a key element in host defense against invasive pathogens NH3 + H2O + 5 ferricytochrome c
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nitrite + 6 ferrocytochrome c + 7 H+
-
Escherichia coli NH3 + 2 H2O + 6 ferricytochrome c
-
?
NO + 5 ferrocytochrome c + 5 H+
-
Escherichia coli NH3 + H2O + 5 ferricytochrome c
-
?
NO + 5 ferrocytochrome c + 5 H+ important role for the enzyme in nitric oxide management in oxygen-limited environments. Nitric oxide is a key element in host defense against invasive pathogens Escherichia coli NH3 + H2O + 5 ferricytochrome c
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
390
-
nitric oxide turnover rate in intact cell Escherichia coli