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Literature summary for 1.6.5.5 extracted from

  • Rao, P.V.; Zigler, J.S.
    Purification and characterization of zeta-crystallin/quinone reductase from guinea pig liver (1992), Biochim. Biophys. Acta, 1117, 315-320.
    View publication on PubMed
Search for more literature for 1.6.5.5

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 4 * 35000, SDS-PAGE Cavia porcellus
140000
-
 gel filtration Cavia porcellus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Cavia porcellus although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics ?
-
 ?
additional information Homo sapiens although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics ?
-
 ?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Cavia porcellus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Cavia porcellus
-
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6
-
-
 Cavia porcellus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-naphthoquinone + NADPH
-
 Cavia porcellus 1,2-naphthoquinol + NADP+
-
 ?
5-hydroxy-1,4-naphthoquinone + NADPH
-
 Cavia porcellus 5-hydroxy-1,4-naphthosemiquinone + NADP+
-
 ?
9,10-phenanthrenequinone + NADPH
-
 Cavia porcellus 9,10-phenanthrenesemiquinone + NADP+
-
 ?
additional information although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics Cavia porcellus ?
-
 ?
additional information although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics Homo sapiens ?
-
 ?
NADPH + H+ + oxidized 2,6-dichlorophenolindophenol
-
 Cavia porcellus NADP+ + reduced 2,6-dichlorophenolindophenol
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 35000, SDS-PAGE Cavia porcellus