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Literature summary for 1.6.3.3 extracted from

  • Poole, L.B.; Higuchi, M.; Shimada, M.; Calzi, M.L.; Kamio, Y.
    Streptococcus mutans H2O2-forming NADH oxidase is an alkyl hydroperoxide reductase protein (2000), Free Radic. Biol. Med., 28, 108-120.
    View publication on PubMed
Search for more literature for 1.6.3.3

Cloned(Commentary)

Cloned (Comment) Organism
-
 Streptococcus mutans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00153
-
 NADH pH 7.0, 25°C Streptococcus mutans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADH + H+ + O2 Streptococcus mutans Nox-1 is a protective protein against oxygen toxicity NAD+ + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus mutans O66266
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Streptococcus mutans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + H+ + O2 Nox-1 is a protective protein against oxygen toxicity Streptococcus mutans NAD+ + H2O2
-
 ?
NADH + H+ + O2 absolute specificity for NADH Streptococcus mutans NAD+ + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
H2O2-forming NADH oxidase
-
 Streptococcus mutans
H2O2-forming reduced nicotinamide adenine dinucleotide oxidase
-
 Streptococcus mutans
Nox-1
-
 Streptococcus mutans

Cofactor

Cofactor Comment Organism Structure
FAD flavoprotein Streptococcus mutans
NADH absolute specificity for NADH Streptococcus mutans

General Information

General Information Comment Organism
malfunction the lack of a significant effect on deletion of the genes from Streptococcus mutans suggests the presence of additional antioxidant proteins in this bacterium Streptococcus mutans
physiological function Nox-1 is a protective protein against oxygen toxicity Streptococcus mutans