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Literature summary for 1.6.3.1 extracted from

  • Zhang, Q.G.; Raz, L.; Wang, R.; Han, D.; De Sevilla, L.; Yang, F.; Vadlamudi, R.K.; Brann, D.W.
    Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation (2009), J. Neurosci., 29, 13823-13836.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.6.3.1

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADPH + H+ + O2 Rattus norvegicus
-
 NADP+ + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADPH + H+ + O2
-
 Rattus norvegicus NADP+ + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
NADPH oxidase
-
 Rattus norvegicus
Nox2
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus NADPH oxidase activity in the hippocampal CA1 region is significantly elevated in placebo versus sham control as early as 30 min after reperfusion, with peak NADPH oxidase activity levels observed at 3 h. 17Beta-estradiol attenuates NADPH oxidase activity in hippocampal CA1 after global cerebral ischemia up