Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Rattus norvegicus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q924V1 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
macula densa | NOX2 and NOX4 are the main isoforms present in macula densa cells | Rattus norvegicus | - |
MMDD-1 cell | - |
Rattus norvegicus | - |
renal epithelium | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + H+ + O2 | - |
Rattus norvegicus | NADP+ + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Nox2 | - |
Rattus norvegicus |
Nox4 | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | NOX2 and NOX4 activity is induced by 70 and 140 mM NaCl | up |
General Information | Comment | Organism |
---|---|---|
physiological function | while macula densa cells express the NOX2 and NOX4 isoforms, NOX 2 is primarily responsible for NaCl-induced O2- generation | Rattus norvegicus |