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Literature summary for 1.6.3.1 extracted from

  • Wang, J.; Li, L.; Cang, H.; Shi, G.; Yi, J.
    NADPH oxidase-derived reactive oxygen species are responsible for the high susceptibility to arsenic cytotoxicity in acute promyelocytic leukemia cells (2008), Leuk. Res., 32, 429-436.
    View publication on PubMed
Search for more literature for 1.6.3.1

Application

Application Comment Organism
medicine pre-treatment of NB-4 cells with inhibitor diphenyleneiodinium blocks arsenic trioxide-induced apoptosis Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
diphenylene iodinium treatment of NB-4 cells blocks basal generation of reactive oxygen species and arsenic trioxide-induced apoptosis Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens NAD(P)H oxidase plays an essential role in maintaining basal levels of reactive oxygen species in NB-4 cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-
NB-4 cell
-
 Homo sapiens
-
SGC-7901 cell
-
 Homo sapiens
-
U-937 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information NAD(P)H oxidase plays an essential role in maintaining basal levels of reactive oxygen species in NB-4 cells Homo sapiens ?
-
 ?