Literature summary for 1.6.3.1 extracted from

Shono, T.; Yokoyama, N.; Uesaka, T.; Kuroda, J.; Takeya, R.; Yamasaki, T.; Amano, T.; Mizoguchi, M.; Suzuki, S.O.; Niiro, H.; Miyamoto, K.; Akashi, K.; Iwaki, T.; Sumimoto, H.; Sasaki, T.
Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival (2008), Int. J. Cancer, 123, 787-792.

Search for more literature for 1.6.3.1

Application

Application	Comment	Organism
medicine	expression of isoform Nox4 mRNA in glioblastomas of WHO grade IV is significantly higher than other astrocytomas of WHO grades II and III. Knock-down of isoform Nox4 expression by RNAi results in cell-growth inhibition and enhances induction of apoptosis by chemotherapeutic agents in cultured glioma cell lines	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	knock-down of isoform Nox4 expression by RNAi results in cell-growth inhibition and enhances induction of apoptosis by chemotherapeutic agents in cultured glioma cell lines	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	isoform Nox4, expression in patients with neuroepithelial tumors	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
astrocytoma cell	expression of isoform Nox4 mRNA in glioblastomas of WHO grade IV is significantly higher than other astrocytomas of WHO grades II and III	Homo sapiens	-
glioblastoma cell	expression of isoform Nox4 mRNA in glioblastomas of WHO grade IV is significantly higher than other astrocytomas of WHO grades II and III	Homo sapiens	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)